New hope for penile fibrosis ED sufferers

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One of the least understood problems that men have as they age is called fibrosis.

Fibrosis is also called sclerosis.

Sclerosis is the term for the hardening of different bodily tissues.

Everyone’s heard of atherosclerosis.

Atherosclerosis is literally the hardening of the arteries.

Each is essentially the same issue.

There can be all kinds of sclerosis going on.

And while each may have a unique circumstance, they’re all related.

So it makes sense that there may be a common cause, and cure for them all.

Aging is usually blamed for these issues because they happen so frequently with age.

As men age, their tissues become less flexible.

The tissues accumulate a sort of scar tissue made up of fibers of protein.

These proteins are called collagen.

The fibers accumulate on their skin and in their organs.

This is where fibrosis comes in.

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When the protein fibers accumulate in the penis, men end up with what’s called penile fibrosis.

The same thing happens throughout the body.

When sclerosis accumulates in the heart, patients have cardiac fibrosis.

As you can see, there are many types, but each are similar in structure.

With so many similarities, it makes sense that there may be a common cause of fibrosis in the whole body.

And there is one.

And serotonin appears to be the culprit.

In this study, researchers took people who had fibrosis occurring throughout their body.

This is called systemic sclerosis.

It’s actually very common even normal in aging people.

In many men, it manifests as arthritis.

The normally flexible tendons in the joints become fibrous and painful.

Nodes may appear and stick out through the skin.

These “digital ulcers” cause those knobs in old peoples’ knuckles.

They’re uncomfortable, but it’s what we expect from aging.

Now here I’m going to digress for a moment and talk about penile fibrosis.

Penile fibrosis interferes with the chambers of the penis that accumulate blood during an erection.

These are called in my simple language, the “erection chambers.”

These erection chambers, together with the arteries that feed the blood, are lined with endothelial tissue.

Endothelial tissue gets diseased with fibrosis, similar to scar tissue buildup.

And this diseased endothelial tissue stops allowing a penis to become erect.

So while the study is focused on knobby knuckles, the problem is exactly the same as what is involved in penile fibrosis.

Researchers gave these men a certain common drug, which affected their serotonin.

The excess serotonin resulted in more, greater and faster development of fibrosis.

That’s the basics of the study.

An interesting point though is that researchers had to stop the study early.

The medication was causing so many problems that it wouldn’t have been ethical to continue.

From this, we can figure that serotonin is a bad thing when it comes to fibrosis.

We can also see that it is often causing penile fibrosis and erectile dysfunction in men.

It is also causing atherosclerosis, hardening of the arteries, heart disease, and many other things.

Serotonin seems to be very damaging.

Many people have an accumulation of excess serotonin causing issues in their bodies.

The process of developing this excess serotonin can be traced easily.

Most of your serotonin is produced in your gut.

From there, the serotonin enters the blood into the platelets, and the platelets go to the lungs.

The lungs have various abilities to separate the serotonin from the platelets.

Then the lungs get rid of the serotonin by combining it with oxygen from the air.

It’s a complicated and beautiful process.

However, if you have too much serotonin, your lungs are not able to get rid of it and it accumulates.

This accumulation is where fibrosis starts.

The solution to fibrosis is in reducing inflammatory serotonin.

You also want to lower the inflammatory hormones such as estrogen, histamine, and cortisol.

This is what’s raising new hope for men who have had long-standing ED due to penile fibrosis.

By reducing serotonin levels, and fixing gut inflammation, men may be able to stop fibrosis.

They may even be able to reverse it in the penile tissues, the arteries, and in the heart.

Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the to ensure accuracy.
Clopidogrel treatment may associate with worsening of endothelial function and development of new digital ulcers in patients with systemic sclerosis: results from an open label, proof of concept study 

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