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Avoiding these foods can help relieve itchy dry skin

Eczema is a condition which causes itchy, dry, inflamed skin.

It is a real pain – and it is a great risk of becoming infected, sometimes with pretty serious bacteria.

There are many causes of eczema, but one which is often overlooked is high histamine – usually coming from the gut.

Researchers investigating the topic found that people with eczema were much more likely to have lower levels of diamine oxidase.

Diamine oxidase is the enzyme which breaks down histamine.

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The human research was carried out at The University of Bonn in Germany. The paper was published in The Journal of Allergy and Clinical Immunology.

Histamine is an irritating substance produced in the body. Many foods also contain histamine.

Histamine can cause many problems including the reactions seen in food intolerances.

Some nonallergic food intolerances are believed to be caused by histamine.

These food intolerances can trigger eczema and other problems elsewhere in the body.

“A diminished histamine degradation based on a reduced diamine oxidase activity is suspected as a reason for non-IgE-mediated food intolerance caused by histamine.”

IgE antibodies are produced by the immune system and they are the trigger for allergies.

These antibodies travel around the body triggering the release of chemicals like histamine.

But histamine can be released without IgE.

We know that eczema can be triggered by IgE.

“Atopic eczema is often complicated by relapses triggered by IgE-mediated allergy to different kinds of food.”

But many people who suffer from eczema do not have any allergies.

“A subgroup of patients with eczema, have no allergies, although these patients report a coherence of food intake and worsening of atopic eczema and describe symptoms that are very similar to histamine intolerance.”

So this research set out to see if their eczema was still triggered by histamine.

The researchers looked at levels of diamine oxidase – an enzyme which destroys histamine.

“We evaluated histamine intolerance symptoms and diamine oxidase levels in 162 patients with atopic eczema compared with 124 patients with histamine intolerance without atopic eczema and 85 healthy people.”

Lower levels of diamine oxidase would lead to higher histamine – and the researchers also looked at histamine levels in the blood plasma.

“Detailed clinical evaluations of characteristic features of atopic eczema and histamine intolerance were performed.”

People with eczema had lower levels of diamine oxidase – they had a decreased ability to dispose of excess histamine.

This could well be the reason for their eczema.

The researchers found that these people were also more likely to suffer with other symptoms of high histamine

Such as headaches, red skin, gastrointestinal problems, and multiple food intolerances.

“Low diamine oxidase and histamine symptoms like headache, flushing, gastrointestinal symptoms, and intolerance of histamine-rich food and alcohol were more common in patients with eczema.”

It makes sense then that reducing histamine could help with eczema and these other symptoms.

“Reduction of both symptoms of histamine intolerance and Atopic Dermatitis could be achieved by a histamine-free diet in the subgroup of patients with atopic eczema and low diamine oxidase serum levels.”

Aside from avoiding foods with histamine (that is a whole lot of foods)…

…there are other ways to increase diamine oxidase and thereby decrease histamine.

This includes getting a little extra vitamin B6 and some extra magnesium.

There are more powerful methods of increasing diamine oxidase if needed.

But for sure, histamine can cause eczema in people who do not have IgE-mediated allergies.

“Higher histamine plasma levels combined with a reduced histamine degradation capacity might influence the clinical course of a subgroup of patients with atopic eczema.”

You should always consult your healthcare practitioner for guidance on medical diagnosis and treatment.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Evidence for a reduced histamine degradation capacity in a subgroup of patients with atopic eczema