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Men: Beware of this dangerous food additive – it slows down metabolism
People who are more active stay lean and healthy.
And did you know that low-level activity is just as important as vigorous exercise?
More and more people are becoming inactive. And this is having a major effect on health.
Recently, researchers discovered that a common food additive can decrease activity levels.
Inorganic phosphate leads to lower levels of activity in lab animals and a decreased desire to exercise in humans.
These researchers carried out their study at UT Southwestern Medical Center. They published their results in the journal Circulation.
Phosphate occurs naturally in many foods.
But many processed foods contain phosphate in its inorganic form… And they add it to these foods for a whole bunch of reasons.
Unfortunately, our bodies absorb it much more easily in this form.
“Inorganic phosphate is used in excess as a preservative and flavor enhancement in processed foods.”
Many popular foods contain high levels of inorganic phosphates.
“Up to 70% of the best-selling grocery items, including cola drinks, prepared frozen foods, dry food mixes, packaged meat, bread, and bakery products, contain inorganic phosphate additives.”
Unfortunately, many Americans are getting three to four times the recommended daily allowance of phosphate because of this.
So these researchers designed this study to look at the effect of inorganic phosphate on physical activity.
“It is unknown whether dietary inorganic phosphate excess contributes to exercise intolerance and physical inactivity.”
The researchers used a device called an actigraph to track activity levels in over 1,600 participants.
In addition, they combined those results with information from a blood test assessing levels of inorganic phosphate.
“We assessed the relationship between serum inorganic phosphate and actigraphy determined physical activity levels.”
People with higher levels of inorganic phosphate tended to get less vigorous activity.
“Higher serum inorganic phosphate was independently associated with reduced time spent in moderate to vigorous physical activity.”
Phosphate was also associated with more sedentary behavior.
“Higher serum inorganic phosphate was independently associated with increased sedentary time.”
Of course, there may be other reasons why people who consume a lot of inorganic phosphates are less active.
Processed foods – high in inorganic phosphates – are often less healthy overall.
So the researchers conducted some animal experiments to focus in on the actual effect of inorganic phosphate additives.
The animal experiments consisted of feeding two groups of mice either high-phosphate or low-phosphate diets.
“Mice were fed either a high (2%) or normal inorganic phosphate (0.6%) diet for 12 weeks.”
At the end of the 12-week diet, they tested the animals on a treadmill.
“Effects of dietary phosphate on exercise capacity, oxygen uptake, serum non-esterified fatty acid, and glucose were measured during exercise.”
Mice given extra inorganic phosphate spent less time on the treadmill and were less active in general.
“Consumption of the high inorganic phosphate diet reduced treadmill duration and spontaneous locomotor activity.”
In addition, the high-phosphate diet caused a lot of changes in the metabolism of those animals.
And the researchers also found those metabolic changes in cell experiments.
Excessive inorganic phosphate alters metabolism and lowers activity levels in humans and mice.
“Our data demonstrate a detrimental effect of dietary inorganic phosphate excess on skeletal muscle fatty acid metabolism and exercise capacity.”
Reducing added phosphate could make people more active, decrease obesity, and lower the risk of cardiovascular disease.
“Dietary inorganic phosphate may represent a novel and modifiable target to increase physical activity.”
But many people get huge amounts of inorganic phosphate in their diet.
Phosphate additives could be leading to inactivity and increased risk of chronic disease.
“This is particularly important because it is estimated that 80% of American adults do not meet the 2008 Centers for Disease Control and Prevention physical activity guidelines for aerobic and muscle strengthening.”
So the researchers want to conduct a human trial to investigate the effect of phosphate restriction on exercise.
“A randomized clinical trial is needed to determine whether dietary Inorganic phosphate restriction improves exercise capacity in otherwise healthy individuals.”
You should always consult a healthcare practitioner about treating and diagnosing health-related problems.
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- High-Phosphate Diet Induces Exercise Intolerance and Impairs Fatty Acid Metabolism in Mice https://www.ahajournals.org/doi/pdf/10.1161/CIRCULATIONAHA.118.037550
- Phosphate Additives in Food—a Health Risk - NCBI https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3278747/
- Phosphate Additives and Your Diet: What You Should Know https://www.healthandwellnessalerts.berkeley.edu/alerts/healthy_living/Phosphate-Additives-and-Your-Diet-What-You-Should-Know_8096-1.html?ET=healthafter%3Ae160454%3A600849a%3A&st=email&s=EYH_180712_001