Men who take this can pass ADHD and autism down
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Weird link between your dad’s use of this and ADHD
I have written before about the probable links between a pregnant mother’s use of certain medications and autism in their children.
Specifically, SSRIs and certain painkillers like acetaminophen seem to increase the risk.
But it’s not just mothers’ medication use that is linked to problems in children.
Several studies now seem to indicate that the use of antidepressant/SSRI medication by fathers in the months previous to impregnating the mother may increase the risk of the child being diagnosed with ADHD.
The rates of ADHD in children have been increasing over the last few decades, with some speculating that this is just due to awareness about the condition – however, it may also be due to the increasing use of SSRIs.
The human research was carried out at Fudan University in Shanghai, China. This paper was published in Pediatrics.
The authors of this study were already aware of research showing that a mother’s use of certain antidepressants could increase the risk of a child having ADHD.
“Maternal prenatal exposure to selective serotonin reuptake inhibitors (SSRIs) may be a risk factor for attention-deficit/hyperactivity disorder (ADHD) in offspring.”
This research was undertaken to see if the same risk relationship existed for a father’s use of these treatments.
The researchers analyzed data taken from government health registers in Denmark.
They had information on almost 800,000 children.
“On the basis of Danish national registers, we conducted a cohort study of 781,470 singletons born between 1996 and 2008 with follow-up throughout 2013.”
The researchers also had information on antidepressant SSRI use in the months leading up to conception.
They set a three-month cut-off point for their analysis.
“The children whose fathers used SSRIs during the last 3 months before conception were identified as the exposed.”
The analysis revealed that children born to fathers who would use SSRIs in the three months before their conception were significantly more likely to have been diagnosed with ADHD.
ADHD risk increased by over one-quarter if the father had used SSRIs.
This was after the numbers had been adjusted to correct for other known risk factors.
“Compared with unexposed children, the exposed had a 26% increased risk of ADHD after adjusting for potential confounders.”
When the researchers extended the time frame to look at fathers who had used SSRIs earlier, they found that SSRIs could be linked to a 35% increase in the risk of ADHD.
“Extending the exposure window to 1 yr before conception, paternal use of SSRIs only during the period of 12 to 3 months before conception was associated with the HR of 1.35.”
The authors speculate that the relationship may be entirely incidental – implying that the fathers have some sort of issue that makes them take SSRIs, contributing to the increased risk of ADHD in children.
“The mildly increased risk of ADHD in offspring associated with paternal SSRI use before conception could probably be due to the underlying indications related to SSRI use.”
The problem is that animal studies show that giving animals treatments like SSRIs, acetaminophen, and ibuprofen lead to neurological and behavioral changes in offspring born to those animals.
Granted, most of this research is in female animals.
But it’s enough to indicate that the relationship between the use of these treatments and ADHD or autism is likely more than incidental.
Proper safety studies on these types of meds are not done, and the major, sometimes intergenerational effects of these are often not known to the public for decades after their release.
Another thing to note is that this research in Denmark identified about 1% of the population as having ADHD.
In the US, the figures are about 10 times higher.
SSRI use is 50-110% higher in the US — so this study could possibly underestimate the role of paternal SSRI use on ADHD in offspring in the US.
You should always consult your healthcare practitioner for medical diagnosis and treatment guidance.
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