Two bad foods that are actually very healthy

Young man drinking coffee in the cafe

They even prevent strokes!

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Two bad foods that are actually very healthy

Ischemic strokes (or just strokes) are extremely scary.

They’re basically clots which stop the blood flow to your brain and vital organs and can cause severe disabilities and even death.

What if you were told that 2 to 3 cups of strong coffee and one daily cocktail could offer significant therapeutic benefits to treat and prevent a stroke?

In all likelihood, most would not believe it.

Both coffee and alcohol have been consistently portrayed as unhealthy beverages.

Of course, there have always been conflicting reports from scientific research, but in general, very few media outlets have praised alcohol and coffee.

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Interestingly, the combination of alcohol (ethanol) and caffeine into a research compound named caffeinol, has been found to have very potent protective benefits:

“Low doses of caffeinol, equivalent to no more than 2 to 3 cups of strong coffee and 1 cocktail, are consistently and highly neuroprotective, are well tolerated, can be added to other therapies to increase the effect of each, and do not interfere with or complicate rtPA therapy. Caffeinol is an appropriate candidate for clinical trial in stroke patients, although it may be less effective in patients with regular alcohol intake.” – Aronowski et al. (2003)

Interestingly, neither ethanol or caffeine alone provided therapeutic alone, but together, their effect was potentiated:

“The combination (caffeinol) was effective after either oral pretreatment or intravenous administration starting up to 2 hours after stroke onset. Ethanol alone aggravated ischemic damage, while caffeine alone was without effect.”

These benefits are not dose-dependent. Individuals who already consume coffee and alcohol do not benefit from extra dosage of “caffeinol.”’

Nevertheless, there are anecdotal reports of homeless men and alcoholics experiencing much lower rates of cardiovascular events.

Caffeine has known vasodilation effects, while ethanol appears to have certain “dissolving” qualities, with specific benefits for cardiovascular mortality and diabetes.

More research is definitely needed, to elucidate precise pathways of action for ethanol and caffeine.

In the meantime, a couple of cups of coffee and a cocktail during happy hour seems like a pleasurable AND protective approach to reducing the risk of stroke.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the https://www.dailymedicaldiscoveries.com/sildenafil-100-mg/ to ensure accuracy.

Aronowski J, Strong R, Shirzadi A, Grotta JC. Ethanol plus caffeine (caffeinol) for treatment of ischemic stroke: preclinical experience. Stroke. 2003 May;34(5):1246-51. doi: 10.1161/01.STR.0000068170.80517.B3. 

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Martin-Schild S, Hallevi H, Shaltoni H, Barreto AD, Gonzales NR, Aronowski J, Savitz SI, Grotta JC. Combined neuroprotective modalities coupled with thrombolysis in acute ischemic stroke: a pilot study of caffeinol and mild hypothermia. J Stroke Cerebrovasc Dis. 2009 Mar-Apr;18(2):86-96. doi: 10.1016/j.jstrokecerebrovasdis.2008.09.015. 

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Piriyawat P, Labiche LA, Burgin WS, Aronowski JA, Grotta JC. Pilot dose-escalation study of caffeine plus ethanol (caffeinol) in acute ischemic stroke. Stroke. 2003 May;34(5):1242-5. doi: 10.1161/01.STR.0000067706.23777.04. Epub 2003 Apr 10. PMID: 12690224.

Zhao X, Strong R, Piriyawat P, Palusinski R, Grotta JC, Aronowski J. Caffeinol at the receptor level: anti-ischemic effect of N-methyl-D-aspartate receptor blockade is potentiated by caffeine. Stroke. 2010 Feb;41(2):363-7. doi: 10.1161/STROKEAHA.109.562900. Epub 2009 Dec 31. PMID: 20044532; PMCID: PMC2896831.

https://pubmed.ncbi.nlm.nih.gov/20044532/

Le Daré B, Gicquel T. Therapeutic Applications of Ethanol: A Review. J Pharm Pharm Sci. 2019;22(1):525-535. doi: 10.18433/jpps30572. PMID: 31604058.

https://pubmed.ncbi.nlm.nih.gov/31604058/

Kim JW, Byun MS, Yi D, Lee JH, Ko K, Jeon SY, Sohn BK, Lee JY, Kim YK, Shin SA, Sohn CH, Lee DY; KBASE Research Group. Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study. PLoS Med. 2020 Feb 25;17(2):e1003022. doi: 10.1371/journal.pmed.1003022. PMID: 32097439; PMCID: PMC7041799.

https://pubmed.ncbi.nlm.nih.gov/32097439/