This one food can cause inflammatory bowel disease in men

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I avoid this one food at all costs

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This one food can cause inflammatory bowel disease in men

Linoleic acid is a highly unsaturated fat.

It’s found in many foods — but vegetable oils are particularly high in this oil.

A hundred years ago people would have gotten a little linoleic acid in their diet.

But these days with the industrial processing of seeds and grains, people eat many times more linoleic acid than they did in the past.

And linoleic acid is highly inflammatory.

Researchers have suspected for decades that linoleic acid may play a role in IBD — inflammatory bowel disease —  ulcerative colitis, and Crohn’s disease.

New research adds strong evidence that this dietary fat does have a large role to play in IBD.

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The human research was conducted at the University of East Anglia at Norwich in the United Kingdom.

The results were published in the British Medical Journal – Gut.

When you eat a fat the body converts it to other things.

Linoleic acid gets converted into arachidonic acid (another fat).

Then arachidonic acid can be converted into a number of inflammatory metabolites, like prostaglandin e2, leukotriene B4, and thromboxane a2.

(Thromboxane a2 is strongly tied to heart diseases, by the way.)

These downstream products of linoleic acid cause generalized inflammation.

This is why researchers suspected that linoleic acid may be involved in inflammatory bowel diseases — where gut cells produce massive amounts of inflammation.

“Metabolites of arachidonic acid have pro-inflammatory properties and are increased in the mucosa of patients with ulcerative colitis.”

The researchers decided to find out if people who eat more linoleic acid in the diet are more likely to have a diagnosis of ulcerative colitis.

To do this, they analyzed data from over 200,000 people. Men and women between the ages of 30 and 74 years old.

The information was taken from a number of studies done in the United Kingdom, Sweden, Denmark, Germany, and Italy.

During the study all of the participants supplied detailed information about their dietary habits.

“Dietary data from food frequency questionnaires were available for 203, 193 men and women aged 30-74 years.”

From this information the researchers made a good estimate of how much linoleic acid individuals consumed.

The participants gave researchers access to their medical records.

The amount of time that medical records were available varied from 1.7 up to 11+ years.

The researchers split people into 2 groups depending on whether or not they developed a new diagnosis of ulcerative colitis during the follow-up period.

“A total of 126 participants developed ulcerative colitis (47% women) after a median follow-up of 4 years.”

Then researchers looked at the risk of developing ulcerative colitis according to dietary intake of linoleic acid.

“These participants were followed up for the diagnosis of ulcerative colitis. Each case was matched with four controls and the risk of disease calculated by quartile of intake of linoleic acid.”

A number of other factors are known to significantly affect the risk of ulcerative colitis.

The researchers took these factors into account before coming to their conclusions.

They found that people who ate a lot of linoleic acid had a much higher risk of being diagnosed with ulcerative colitis.

The people in the highest intake were 2.5 times more likely to receive a diagnosis than those who ate the least.

“The highest quartile of intake of linoleic acid was associated with an increased risk of ulcerative colitis (Odds ratio 2.49).”

The average increase in ulcerative colitis risk when moving from one quartile to a higher intake was 32%.

If there were no known mechanisms by which linoleic acid might cause inflammatory bowel disease then this might not be a causal relationship.

The fact that linoleic acid leads to inflammatory compounds which are found in the gut cells of people with ulcerative colitis makes it very likely that linoleic acid is a major causal factor in this disease.

“The data support a role for dietary linoleic acid in the aetiology of ulcerative colitis.”

This polyunsaturated fat may play a significant role in one third of ulcerative colitis cases.

“An estimated 30% of cases could be attributed to having dietary intakes higher than the lowest quartile of linoleic acid intake.”

The findings make a strong case for lowering your intake of polyunsaturated fats.

Many foods have some linoleic acid — but most of the dietary linoleic acid comes from vegetable oils- – seed oils and grain oils.

I think it is better to get you dietary fat from dairy, coconut oil and ruminant animals.

You should always consult a healthcare practitioner about treating and diagnosing health-related problems.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.


Linoleic acid, a dietary n-6 polyunsaturated fatty acid, and the aetiology of ulcerative colitis: a nested case-control study within a European prospective cohort study.–control+study+within+a+European+prospective+cohort+study