P. gingivalis bacteria starts in the mouth and travels to the brain — but this delicious brew stops it
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This drink kills the bacteria that leads to Alzheimer’s and dementia
If you have health problems, you can bet that bacteria are involved.
The major cause of death in most animals is sepsis.
Sepsis results from toxic bacteria infecting the body at large (leaking from their home in the gut).
The immune system tries to kill the bacteria, but if there’s too much bacterial load it will kill the infected organism.
Over the last two decades we’ve discovered that many of the most common diseases are probably caused by bad bacteria.
Obesity, type II diabetes, cancer, Parkinson’s, and Alzheimer’s disease are all strongly tied to toxic bacteria.
These bacteria usually leak from the gut into the bloodstream poisoning the organs.
But in the case of Parkinson’s and Alzheimer’s, we know that they can also come from the mouth.
The bacteria which causes periodontal disease (Porphyromonas gingivalis) is a major suspect in the development of dementia.
For example, in January of 2019 Science Advances published research on Porphyromonas gingivalis and Alzheimer’s.
This dangerous bacteria causes periodontitis — gum disease.
But it’s also present in many people with seemingly good oral health status.
“P. gingivalis is mainly found during gingival and periodontal infections; however, it can also be found at low levels in 25% of healthy individuals with no oral disease.”
These researchers tested for the bacteria in Alzheimer’s patients.
They tested for traces of the bacteria in the brains of Alzheimer’s patients and compared those levels against the levels of tau proteins – a sure sign of Alzheimer’s.
The bacteria and its products (gingipain) were strongly tied to Alzheimer’s in these human investigations.
“Toxic proteases from the bacterium called gingipains were also identified in the brains of Alzheimer’s patients, and levels correlated with tau and ubiquitin pathology.”
Later, the researchers exposed live mice to the bacterial toxin, causing the same Alzheimer’s like changes.
“Oral P. gingivalis infection in mice resulted in brain colonization and increased production of Aβ1–42, a component of amyloid plaques. Further, gingipains were neurotoxic in vivo and in vitro, exerting detrimental effects on tau, a protein needed for normal neuronal function.”
Blocking the mouth-sourced bacterial toxin protected the mouse brains.
“Gingipain inhibition reduced the bacterial load of an established P. gingivalis brain infection, blocked Aβ1–42 production, reduced neuroinflammation, and rescued neurons in the hippocampus.”
The chemical-based blockers used in this study are not available yet…
But scientists have just discovered that there is a compound in coffee which beats down this Porphyromonas gingivalis bacteria in the same way.
The lab experiments were carried out at the Institute of Oral Sciences, College of Oral Medicine, Chung Shan Medical University, Taichung, Taiwan.
The results were published in the journal Nutrients.
The research was based on previous observations that coffee could improve oral health.
“Previous research found that coffee had a protective effect on periodontal disease (gum disease).”
The researchers wanted to identify which element of coffee might provide the antibiotic effect.
The experiments were carried out on the P. gingivalis bacteria — the cause of gum disease and the prime suspect in Alzheimer’s.
“We aim to investigate whether coffee extract and its primary phenolic acid, chlorogenic acid affect the growth and protease activity of P. gingivalis.”
The researchers used a coffee extract in some of the experiments.
In other experiments they used purified chlorogenic acid — a major active component of coffee.
The researchers tested the effects of both of these substances on the growth and activity of the bacteria.
Chlorogenic acid from coffee inhibited the growth of P. gingivalis.
Confirming that coffee has an antibiotic effect against this lethal bacteria.
“Chlorogenic acid at high concentrations resulted in a longer-lasting inhibitory effect on P. gingivalis viability and significantly reduced associated protease activity.”
The coffee extract was also affected at thwarting the bacteria’s growth.
“In addition, coffee extract inhibits the proliferation of P. gingivalis, which may partly be attributed to the effect of chlorogenic acid.”
Coffee consumption may lower the risk of Alzheimer’s by fighting the bacteria that likely cause this disease.
You should always consult a healthcare practitioner about treating and diagnosing health-related problems.
—-Important Message For Men Who Don’t Want Alzheimer’s—-
Beware the killer lipid lurking in the U.S. food supply — creates amyloid plaques in the brain that lead to Alzheimer’s
Nearly 100 years ago, manufacturing companies started contaminating food with a toxic killer chemical…
And now today, it’s in almost every single food item we eat.
It’s in fast food, organic food, so-called “healthy” foods — every single food at the grocery store is full of this toxic chemical.
And it’s doing terrible things to men’s bodies…like forming amyloid plaques that lead to Alzheimer’s and dementia…
And unfortunately, there’s no easy way to avoid eating this killer lipid nowadays because it’s in too much of the food supply!
BUT — I have discovered a way to safely destroy this killer lipid once it enters our bodies — BEFORE it gets in the bloodstream and wreaks havoc in our cells and organs.
Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors
Potential Oral Health Care Agent from Coffee against Virulence Factor of Periodontitis