Strange mushroom may make brain cells “immortal”

Cheerful, attractive brunette girl - in pink pajamas and with a white towel on her head - cutting mushrooms

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Strange mushroom may make brain cells “immortal”

Cordyceps mushroom supplements are used for treating asthma, sexual problems, and low energy. I love taking them occasionally myself. They are awesome!

And the mushroom is reported to increase athletic performance.

But it also has protective effects on the brain. 

And recently, researchers looked into the effect of the cordyceps mushroom on Parkinson’s disease.

The results were very promising… An extract from the mushroom alleviated Parkinson’s disease symptoms in rats.

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The animal experiments were carried out at the Heze Municipal Hospital, Heze, Shandong, China. Life Sciences published the results.

Parkinson’s disease is associated with a very specific type of brain damage.

Brain cells that produce dopamine in one particular region of the brain die off in Parkinson’s disease.

“Parkinson’s disease is characterized by the loss of dopaminergic neurons in the substantia nigra.”

The psychological and physical symptoms of Parkinson’s disease are largely determined by the health of these brain cells.

Prior research has shown that a chemical in this mushroom (cordycepin) can protect brain cells.

Cordycepin is also known for its anti-cancer effects.

“Cordycepin, a small molecule extracted from cordyceps sinensis, has neuroprotective, anti-inflammatory, antioxidant, and anti-tumor properties.”

Researchers were interested in the effect of this chemical on the progression of Parkinson’s disease – because of its known protective effect on brain cells.

“In this study, we explored the possible beneficial effects of cordycepin on Parkinson’s disease.”

The researchers conducted experiments using rats.

In these experiments, the researchers attempted to create Parkinson’s disease in the animals.

They gave the rats a toxic chemical known as MPTP.

MPTP causes Parkinson’s-like behaviors. It also creates the same type of damage to the brain that we see in Parkinson’s disease.

“Parkinson’s disease rat models were established via MPTP injection.”

After the animals were exposed to the toxin, some of them were given the mushroom-based supplement.

The researchers conducted a number of behavioral tests on the animals to look for signs and symptoms of Parkinson’s disease.

The chemical toxin caused motor problems and the loss of brain cells characteristic of Parkinson’s.

“MPTP injection introduced motor disorders and the loss of dopaminergic neurons.”

Animals given the mushroom extract were protected against much of the damage from the Parkinson’s-causing chemical.

“Cordycepin treatment alleviated these MPTP-induced changes.”

The researchers then conducted cell experiments. 

And these experiments showed that the mushroom-based chemical could lower the inflammation associated with Parkinson’s.

“Cordycepin alleviated Parkinson’s disease symptoms by inhibiting inflammatory signaling pathways in vivo and in vitro.”

Cordyceps mushrooms have been used all over the world for thousands of years. 

They became famous back in 1993 when a number of Chinese athletes shattered track and field records after supplementing with cordyceps sinensis.

The compound used in these experiments was originally discovered in C. sinensis

This mushroom parasitizes caterpillars – killing them and growing on their bodies.

Those mushrooms are traditionally gathered in mountainous regions in Asia…

And they can sell for $20,000 per kilogram!

Since 1993, the cordycepin compound used in this study has also been found in other cordyceps mushrooms… 

And these mushrooms can be farmed, so they make cordycepin much cheaper to produce.

Cordyceps mushroom supplements are now becoming very popular. 

Many people find that they can improve their mental sharpness, energy levels, and athletic performance.

In future, the mushrooms may be used in the treatment of Parkinson’s disease and cancer.

You should consult a healthcare practitioner about diagnosing and treating any health-related problems.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.