Most men who take this treatment end up impotent

A young man alone and worried

…sometimes permanently…

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Propecia often causes very nasty side effects.

It reduces DHT and that causes terrible erections problems for many men, often lasting for years.

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Most men who take this treatment end up impotent 

Finasteride is a medication used to treat enlarged prostate and hair loss. It’s also called Propecia.

The treatment hit the market in 1992 and it is now one of the top 100 most-prescribed meds in the U.S.

For years, men have been complaining about a whole host of side effects allegedly caused by this treatment.

Most commonly, finasteride is alleged to cause depression, poor brain function, and an array of sexual problems.

What’s more, many men believe that these symptoms persist long after they have stopped taking finasteride.

In recent years, some researchers have begun to look into the topic of “post-finasteride syndrome”… 

Much of this research supports the idea that finasteride could be a very dangerous treatment.

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This human research took place by researchers from the Hunter-Bellevue School of Nursing, New York. The American Journal of Men’s Health published the results.

Finasteride is a treatment that acts on enzymes related to hormone production. 

It is used because it stops the body from converting testosterone to DHT.

DHT has been implicated in the number of health problems in men… 

It is thought to increase the risk of prostate problems and male pattern baldness.

(Those claims are controversial, but that’s not the topic of this article…)

“Finasteride prevents the conversion of testosterone to DHT and has been used for more than 20 years in the treatment of male pattern hair loss.”

This research was designed to investigate the alleged existence of post-finasteride syndrome. 

This is a group of symptoms that are alleged to occur even long after a person has stopped using finasteride.

“We sought to characterize sexual and nonsexual adverse events that men reported experiencing at least three months after stopping the treatment.”

The research consisted of an online survey asking men about the cluster of symptoms that make up post-finasteride syndrome.

“We constructed an Internet survey targeting six domains.”

Finasteride use has been linked to mental and sexual problems.

The researchers asked about the following aspects of the participants’ lives after cessation of finasteride:

“Physical symptoms, sexual libido, ejaculatory disorders, disorders of the penis and testes, cognitive symptoms, and psychological symptoms.”

The study included information from over 100 men aged 21 to 62 years old (average age 24).

“Responses from 131 generally healthy men who had taken finasteride for male pattern hair loss were included in the analysis.”

The study found that there were adverse effects in all of the areas assessed, even long after finasteride use had ceased.

Adverse effects persisted in each of the domains, indicating the possible presence of a ‘post-finasteride syndrome.’”

Many of the men experienced the problems that are alleged to occur with finasteride use:

  • Physical symptoms
  • Problems with libido
  • Ejaculatory disorders
  • Disorders of the penis and testes
  • Cognitive symptoms
  • Psychological symptoms

Finasteride lowers the production of DHT – a hormone that some researchers believe can cause baldness are prostate problems.

But DHT is also critical to male health… 

It is one of the two most important male hormones, the other being testosterone.

Finasteride also affects other hormones. 

Finasteride lowers the production of a hormone called allopregnanolone.

Allopregnanolone Is a hormone that is mainly active in the brain

This hormone has garnered a lot of attention recently for its ability to lower anxiety and improve mental health.

Allopregnanolone is actually being studied as a potential antidepressant treatment.

Allopregnanolone is also important for sleep and memory – central problems in post-finasteride syndrome.

“Several studies suggest that neurosteroids and neuroactive steroids like allopregnanolone…may be involved in the modulation of memory processes and sleep.”

So the sexual and mental side effects of finasteride are not unexpected if you understand how it works.

It may be that supplementing allopregnanolone and DHT or their precursors could help men suffering from post-finasteride syndrome. 

Hopefully the findings of this study will force further research into such questions.

You should always consult a healthcare practitioner about diagnosing and treating any health-related problems.

—-Important Message—-

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.


Persistent Sexual, Emotional, and Cognitive Impairment Post-Finasteride: A Survey of Men Reporting Symptoms