Is Metformin safe for diabetics?

Is Metformin safe for diabetics?

Metformin is the most prescribed drug for diabetics and pre-diabetics.

This is so despite very large studies that show Metformin doesn’t actually help reduce mortality in diabetes at all.

In fact, there are plenty of reasons to question if it is even safe and is Metformin bad for you instead.

In this newsletter, I want to show you two studies on metformin.

The first study is a very large meta-study.

I don’t normally use meta-studies, but in this case, I think it’s quite valuable.

The researchers were honest.

They had a tough time because these kinds of studies are very difficult to do if they are extremely damaging to the prospects of a drug.

There are just too many drug companies clamoring for drug company cash.

It doesn’t make it easy for honest scientists.

So let me give you their conclusion.

Metformin did not significantly affect the primary outcomes all-cause mortality, and cardiovascular mortality.

This is their finding after looking at 13,110 patients.

Some patients took Metformin, and then some patients did not.

All of the patients were diabetic or pre-diabetic.

In other words, Metformin doesn’t work.

As to why metformin doesn’t work, let’s look at a recent study.

The first thing to realize about Metformin is that it accumulates in the energy-producing parts of each cell, the mitochondria.

Mitochondria are responsible for breathing, energy, and life.

There are thousands of mitochondria in some cells.

And virtually all cells in the body require mitochondria to stay alive.

The researchers find that mitochondria

accumulate metformin by 1000-fold in the mitochondrial matrix, relative to in serum.

When the Metformin is in the mitochondria, it has very disturbing effects

ATP hydrolysis is inhibited by metformin.

There is a fabulously complex biochemical chain reaction that produces ATP.

And researchers think ATP is the energy vehicle for the whole body.

Metformin interferes with the production of ATP in the mitochondria.

It also interferes with one of the functions of folate, a B vitamin.

Metformin disrupts folate-related one-carbon metabolic pathways.

Metformin interferes with so many different metabolic processes that often it leads to a vitamin B12 deficiency.

And it can lead to a possible folate deficiency.

Metformin also interferes with the creation of glucose from protein.

If the body is not getting enough sugar, it must make its own sugar to live.

That process of producing sugar in the body is gluconeogenesis.

Metformin stops gluconeogenesis, potentially lowering blood sugar and killing cells.

Recently, mitochondrial glycerophosphate dehydrogenase has also been reported to be inhibited by metformin, and this effect has been proposed as the origin of metformin’s ability to suppress gluconeogenesis.

So, you may be thinking that the point is to lower blood sugar.

But the problem in diabetes isn’t that there is too much sugar, it is that the body doesn’t metabolize it.

Metformin does not solve that problem — frankly, it interferes with so many things but does not help at all.

To solve diabetes, you don’t want to lower your sugar.

You need to solve the problem stopping your body from processing sugar and allowing it to build up in the body.

Now you can see why Metformin has not led to a lower death rate from diabetes.

And why you may want to reconsider taking Metformin in consultation with your doctor.



Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Reappraisal of Metformin Efficacy in the Treatment of Type 2 Diabetes: A Meta-Analysis of Randomised Controlled Trials 

Effects of metformin and other biguanides on oxidative phosphorylation in mitochondria 


  1. hello there and thank you for your information – I’ve certainly picked up something new from right here. I did however expertise a few technical issues using this site, as I experienced to reload the website a lot of times previous to I could get it to load correctly. I had been wondering if your hosting is OK? Not that I am complaining, but slow loading instances times will sometimes affect your placement in google and can damage your quality score if ads and marketing with Adwords. Well I am adding this RSS to my email and could look out for a lot more of your respective fascinating content. Make sure you update this again soon..

  2. 829158 265658My California Weight Loss diet invariably is an cost effective and versatile staying on your diet tv show produced for individuals who locate themselves planning to drop extra pounds and furthermore ultimately keep a considerably healthier habits. la weight loss 896349

  3. 401545 75746Hi! Someone in my Facebook group shared this internet site with us so I came to check it out. Im certainly loving the data. Im book-marking and will probably be tweeting this to my followers! Outstanding weblog and wonderful style and style. 136321

  4. 159440 733432You could surely see your enthusiasm within the work you write. The world hopes for much more passionate writers like you who arent afraid to say how they believe. Always go following your heart. 749953

  5. 617 137012Superb post but I was wanting to know in the event you could write a litte far more on this subject? Id be quite thankful in case you could elaborate just a little bit much more. Thanks! 238936

  6. 858616 591110I ran into this page accidentally, surprisingly, this really is an excellent website. The site owner has done a great job writing/collecting articles to post, the info here is actually insightful. You just secured yourself a guarenteed reader. 445761

  7. 294313 401600You need to be really astute at research and writing. This shows up inside your original and unique content material. I agree together with your primary points on this subject. This content should be seen by a lot more readers. 543487

  8. 99888 613287Hiya! Fantastic weblog! I happen to be a every day visitor to your internet site (somewhat a lot more like addict ) of this website. Just wanted to say I appreciate your blogs and am looking forward for far more! 611731

  9. 56558 842553Exceptional weblog here! In addition your internet internet site rather a whole lot up fast! What host are you using? Can I get your affiliate hyperlink for your host? I wish my site loaded up as quick as yours lol. 339591

  10. 951425 102963Oh my goodness! a fantastic post dude. Thank you Even so I will probably be experiencing issue with ur rss . Dont know why Can not subscribe to it. Will there be any person getting identical rss dilemma? Anybody who knows kindly respond. Thnkx 955747

  11. 329977 442325This really is a proper blog for would like to uncover out about this subject. You realize a great deal its almost challenging to argue along (not that I personally would wantHaHa). You really put the latest spin with a topic thats been discussed for a long time. Wonderful stuff, just fantastic! 830084

  12. Understand by watching the advantages. This doesn’t mean just seated around and finding this game along with your friends. Get a gamer who plays the identical place as you may and enjoy the direction they play. Analyze the way that they relocate their feet, and what selections they make in the area. Make an effort to replicate them in your own online game.

  13. If you want to require the whole family in the bet on soccer, allow it to be flag soccer that you just play. Flag basketball is much less dangerous than dealing with, so it can be useful for all generations of athletes and all of sexes as well. You may have a entire bunch of household bonding time using the game.

  14. As a receiver, it is very important be really speedy and also a great deal of pace. To increase your pace set up a nicely identified operating location. Accomplish this by placing 2 cones 10 yards apart. Operate at top rated velocity involving the two cones and track your time and effort. Now, commence attempting to overcome that time. Sprinting such as this has many positive aspects, including an velocity of takeoff rates of speed.

  15. Get used to actively playing away from your weaker ft .. If you’re like many sportsmen, you’ll prefer one foot above an additional. It’ll tend to be the ft . that you pivot on and utilize for working fakes. If you wish to mix up the rival masking you, delight these with some goes utilizing your weakened side. It’ll offer you some true edge.

  16. The world is like a hillside. As long as you are not standing at the apex, someone will always be taller than you. When you look up for a long time, you must look down at the right time. We are all ordinary people.

  17. Manisa evden eve nakliyat sektöründe yapmış olduğumuz çalışmalar ile Taşımacılık alanında güven ve Konfor adında birçok müşteriyi yeni yuvasına kavuşturuyoruz. Yer mekan gözetmeksizin talep üzerine evinize gelen ekip arkadaşlarımız dahilinde ürünleriniz incelenir daha sonra taşınılacak eve eşyalarınız kırılma olanaksızın sefk edilir.

  18. Good day! This is my 1st comment here so I just wanted to give aquick shout out and say I really enjoy reading through your posts.Can you recommend any other blogs/websites/forums that go over thesame topics? Many thanks!

  19. I just want to mention I’m all new to blogs and certainly savored you’re web site. More than likely I’m want to bookmark your site . You surely have good writings. Appreciate it for sharing your web page.

  20. Greetings from Los angeles! I’m bored to tears at work so I decided to check out your blog on my iphone during lunch break. I enjoy the knowledge you provide here and can’t wait to take a look when I get home. I’m surprised at how fast your blog loaded on my cell phone .. I’m not even using WIFI, just 3G .. Anyhow, awesome blog!

  21. I have been browsing online more than three hours today, yet I never found any interesting article like yours. It’s pretty worth enough for me. In my view, if all web owners and bloggers made good content as you did, the internet will be much more useful than ever before.

  22. Woah! I’m really enjoying the template/theme of this blog. It’s simple, yet effective. A lot of times it’s hard to get that “perfect balance” between usability and visual appeal. I must say that you’ve done a very good job with this. Also, the blog loads very fast for me on Opera. Outstanding Blog!|

  23. Thank you for some other excellent article. Where else could anybody get that typeof info in such an ideal approach of writing? I have apresentation subsequent week, and I’m on the look for such information.

  24. I was curious if you ever thought of changing the page layout of your website? Its very well written; I love what youve got to say. But maybe you could a little more in the way of content so people could connect with it better. Youve got an awful lot of text for only having 1 or two pictures. Maybe you could space it out better?|

  25. Hi there, i read your blog occasionally and i own a similar one and i was just wondering if you get a lot of spam remarks? If so how do you reduce it, any plugin or anything you can suggest? I get so much lately it’s driving me insane so any support is very much appreciated.|

  26. Hi, I do believe your blog might be having internet browser compatibility problems. When I look at your blog in Safari, it looks fine however, when opening in IE, it’s got some overlapping issues. I merely wanted to give you a quick heads up! Besides that, excellent website!|

  27. I was curious if you ever thought of changing the structure of your blog? Its very well written; I love what youve got to say. But maybe you could a little more in the way of content so people could connect with it better. Youve got an awful lot of text for only having one or 2 pictures. Maybe you could space it out better?|

3 Trackbacks / Pingbacks

  1. Google
  2. Google
  3. Homepage

Leave a Reply

Your email address will not be published.