Elevated aldosterone levels in men and how to lower it

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Too much aldosterone hurts the heart — here’s how to lower your levels…

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Elevated aldosterone levels in men and how to lower it

Aldosterone is a steroid hormone produced in the adrenal cortex.

Compared with other common hormones like testosterone or even adrenaline, aldosterone is virtually unknown to the general population.

Ray Peat, PhD has referred to aldosterone as the “opposite of progesterone,” because in many ways they are two side of the same coin:

“Even before aldosterone was identified, progesterone’s role in regulating the salts, water and energy metabolism was known.”  – Peat (2007)

Aldosterone is also closely related to the maintenance of fluids. It plays an important role in the body’s ability to regulate blood pressure, among many, many other functions.

However, aldosterone can easily become elevated, notably in the case of dietary salt restriction…

…and elevated aldosterone tends to lead to every bad pathological change which progesterone protects against.

In particular, elevated aldosterone levels are very dangerous with respect to various aspects of cardiovascular health:

It has been known for many years that decreasing sodium intake causes the body to respond adaptively, increasing the renin-angiotensin-aldosterone system (RAAS). The activation of this system is recognized as a factor in hypertension, kidney disease, heart failure, fibrosis of the heart, and other problems. – Peat (2007)

A 2011 Czech study referred to aldosterone as an “endogenous cardiovascular toxin:”

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According to this review paper, even a “slight increase in aldosterone concentrations in cardiac tissues adversely affects myofibrils (muscle fibrils) as well as coronary artery function.”

In another study by Sun et al., aldosterone was found to be “proinflammatory and fibrogenic (inducing fibrosis)” in the cardiovascular tissues of rats.

The researchers found that these effects could be alleviated by spironolactone, a common aldosterone antagonist often used for cardiovascular disease prevention.

As it turns out, spironolactone is merely a progesterone-derivative.

Meaning spironolactone was synthesized from progesterone itself, and shares much of its parent molecule’s characteristics.

This suggests that a progesterone deficiency is probably causing the harmful cardiovascular changes associated with elevated aldosterone.

Bottom line: salt your food to taste, and take the general steps to eat a very nutritious diet, which will increase your natural production of progesterone.

If need be, you can take a natural progesterone supplement, even applied topically, just to be on the safe side.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.


Horký K. Aldosteron jako endogenní kardiovaskulární toxin a moznosti jeho terapeutického ovlivnení [Aldosterone as an endogenous cardiovascular toxin and the options for its therapeutic management]. Vnitr Lek. 2011;57(12):1012-1016.



Sun Y, Zhang J, Lu L, Chen SS, Quinn MT, Weber KT. Aldosterone-induced inflammation in the rat heart : role of oxidative stress. Am J Pathol. 2002;161(5):1773-1781. doi:10.1016/S0002-9440(10)64454-9



Peat, Raymond. Salt, energy, metabolic rate, and longevity (2007) http://raypeat.com/articles/articles/salt.shtml