Curcumin lowers estrogen and lowers inflammation

Curcumin lowers estrogen and lowers inflammation


Many men are taking curcumin these days.

So I thought you might be interested in a discussion about curcumin benefits, safety, and usage.

Curcumin is a compound that occurs in very high amounts in the yellow spice called turmeric.

Turmeric is a rhizome (think root) like ginger is, and the powder is inexpensive and easy to get.

Rather than get curcumin with a turmeric dosage, you get the powdered curcumin supplement.

The purified powder is called curcumin and is still yellow and can stain everything it touches.

By the way: beware of ruining your clothes!

Since it’s plentiful, cheap, and easy to get, there are questions that need answers.

First is curcumin estrogenic like many plant compounds?

Here’s the first piece of good news.

There is a good study that shows curcumin is not estrogenic.

This is a study done of tissue in the test tube rather than in human patients.

But it does give us some indication that exposure to curcumin causes estrogen levels to fall in tissues.

E2 level was lower after treatment with curcumin.

So that’s the good news about curcumin, it is not estrogenic and may even be a mild way to lower estrogen somewhat.

But there’s the next question, does curcumin lower inflammation?

Does curcumin reduce pain?

The answer seems to be — maybe.

In this study, curcumin did not reduce arthritis pain.

But in another study, curcumin worked better than NSAIDs to reduce arthritis pain:

The curcumin group showed the highest percentage of improvement… significantly better than the patients in the diclofenac sodium group.

Ok, so it’s possible that it also helps reduce arthritis pain.

But it’s not all good news.

One problem with curcumin has difficulty traveling through the gut into the body.

In a mouse study, only a tiny amount of the curcumin that the mice swallowed made it into their bloodstream.

But injections of curcumin were 50 times more effective.

And intravenous curcumin resulted in blood levels:

50-fold higher than curcumin dose administered orally.

The most common way to get curcumin absorbed is to take it with black pepper extract.

According to this study, piperine increased absorption 20 times — even when taken orally.

Here’s what I would do with this information.

I would probably consider curcumin as part of my strategy if I felt a need to reduce prostate cancer tumor size.

And I would consider it as a help for arthritis and other pain.

But I probably would also look for metabolic solutions that are far more powerful than curcumin.

 

 


Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Curcumin inhibits endometriosis endometrial cells by reducing estradiol production 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941414/ 

Preliminary study on antirheumatic activity of curcumin (di feruloyl methane) 
http://web.b.ebscohost.com/abstract?direct=true&profile=ehost&scope=site&authtype=crawler&jrnl=09715916&AN= 91259731&h=vCEerJEaJRKs6I2g0b8PIOMbJ%2bvVl4wIEAolLVZFodQREqw dn9LVvFf%2bFfwxkXFcYIpvhievTVZiq7%2bW%2fPcaw%3d%3d&crl= c&resultNs=AdminWebAuth&resultLocal=ErrCrlNotAuth&crlhashurl =login.aspx%3fdirect%3dtrue%26profile%3dehost%26scope %3dsite%26authtype%3dcrawler%26jrnl%3d09715916%2 6AN%3d91259731 

A Randomized, Pilot Study to Assess the Efficacy and Safety of Curcumin in Patients with Active Rheumatoid Arthritis 
http://onlinelibrary.wiley.com/doi/10.1002/ptr.4639/full

Influence of piperine on the pharmacokinetics of curcumin in animals and human volunteers 
https://www.ncbi.nlm.nih.gov/pubmed/9619120 

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