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Prostate tissue and human testicle tissue have a weird receptor called the Farnesoid X Receptor.
This receptor does a lot of things, and we’ll go over a few today.
It plays a role in cancer preventing while it helps increase testosterone levels.
The Farnesoid X Receptor may even help Type 2 diabetics recover their insulin function.
And coffee may be a clue as to how to activate this receptor.
In fact you can boost testosterone levels with coffee because of this receptor.
The farnesoid X receptor, or FXR, is present in many places in the body.
It’s in the liver, kidneys, testicles, prostate, and probably in the erection chambers in the penis.
When the FXR is activated, it lowers the body’s disposal of DHT, androsterone, and other male androgens.
So put another way, when your FXR is not activated, your body will often dispose of DHT and other androgens.
You’ll just pee them away.
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The FXR activates when in contact with bile acids.
Bile acids, of course, circulate in our intestines and help us digest food.
But bile acids also end up in our bloodstream.
Exposure to bile acids activates our FXR.
But there’s another benefit to this exposure.
When the FXR is activated, it tends to lower prostate cancer and prostate inflammation.
It seems to be very important activate the FXR.
So to sum up what happens when the FXR is active there are two points.
One is that it tends to maintain high levels of male androgens.
It’s especially effective for testosterone, androsterone and all the other metabolites that make men perform and have a high libido.
And second, the FXR tends to lower the growth of cancers in our body.
It seems to work particularly well against prostate cancer and prostate inflammation.
So it seems to be helpful to activate our Farnesoid X Receptors or FXRs.
Two safe foods that activate FXR are taurine and certain types of coffee.
I’ve talked about taurine in the past.
Taurine is present in high amounts in certain seafood, such as shrimp and scallops.
And it’s also present in liver meat.
You can also purchase it as an inexpensive supplement.
Red Bull and other energy drinks also have taurine — Red Bull has about 1000 mg of taurine.
Certain preparations of coffee contain a lot of a compound called cafestol.
Cafestol activates FXR.
So first, this is a study that was done on tissues rather than inside the human body.
But I feel it’s a very good study.
Cafestol is present in all coffee but is not able to pass through the typical coffee filter.
So there are types of coffee contain large amounts of cafestol.
You can get good amounts of cafestol in instant coffee, either caffeinated or decaffeinated.
French press coffee is another great source of cafestol, either caffeinated or decaffeinated.
And it’s even better if you use the decaffeinated version that is “CO2 extracted” or “water extracted.”
Turkish style coffee where the ground coffee is boiled with the water also contains the cafestol.
Basically, it’s in any coffee preparation where the coffee does NOT have to go through a liner.
The researchers determined that:
Two bioactive substances in coffee, cafestol and caffeic acid, acutely increased insulin secretion.
Both caffeic acid and cafestol had the potential to chronically enhance glucose-stimulated insulin secretion.
In addition, we demonstrated that chronic exposure to cafestol increased glucose uptake into human skeletal muscle cells to a similar extent as the antidiabetic agent rosiglitazone.
Cafestol and caffeic acid both hold the potential to acutely and chronically increase insulin secretion and cafestol also to improve insulin sensitivity by increasing the glucose uptake in muscle cells.
This is great news!
The components in coffee, cafestol and caffeic acid, both help reduce Type 2 Diabetes.
And it works even if they drink decaf!
Caffeine and Type 2 Diabetes aren’t considered a good relationship, but the FXR let’s them drink coffee and benefit.
It puts to rest worrying is coffee good for Type 2 Diabetes.
But getting back to the original discussion of the farnesoid X receptor.
Cafestol is a very powerful activator of the FXR.
So it is quite possible that drinking coffee high in cafestol will do more than help maintain a healthy response to insulin.
It will also lower the chances of prostate cancer and inflammation in the prostate.
Plus it raises testosterone and male androgen levels — keeping them at a higher healthier level.
Who knew that coffee could do so much?
https://www.ncbi.nlm.nih.gov/pubmed/17988216
Cafestol, a Bioactive Substance in Coffee, Stimulates Insulin Secretion and Increases Glucose Uptake in Muscle Cells: Studies in Vitro
http://pubs.acs.org/doi/full/10.1021/acs.jnatprod.5b00481
Cafestol extraction yield from different coffee brew mechanisms
http://www.sciencedirect.com/science/article/pii/S0963996912002360
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