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I’ve talked about penile fibrosis a number of times.

I’ve talked about what causes penile fibrosis and ways to prevent it.

And the great thing is that because of our work here, more doctors are now becoming aware of penile fibrosis.

In the old days, they assumed that only people with Peyronie’s had any fibrosis.

Peyronie’s disease is what it’s called when there is an abnormal curve to the penis.

It’s caused by scar tissue in the penis that eventually causes a curved penis.

It can start with finding a lump on penis shaft, and lead to a much more severe curve.

This fibrous tissue can produce a curve so severe that it prevents penetration from being possible during sex.

For a long time, doctors thought this Peyronie’s disease was the thing caused by fibrosis.

We’ve known better for ages, and we’ve been doing our best to spread the word.

And now we’re seeing that the work we’re doing is paying off.

More doctors and patients are aware that they may have penile fibrosis even if they don’t have a real bendy male member.

Dr. Jon Pryor, urology chair at the University of Wisconsin, says that about 22% of aging men have penile fibrosis.

And they don’t know it.

These men will often go to their graves wondering why they had such persistent and unfixable erectile dysfunction.

And along it was the penile fibrosis that could have been fixed.

It is not surprising that there is a myriad of oral “cocktails” that have been touted for medical management of penile fibrosis.

These include vitamin E, Potaba, tamoxifen, colchicine, L-arginine, carnitine, pentoxifylline, and phosphodiesterase type-5 inhibitors.

Unfortunately, virtually all of them show no clinical benefit.

So there are no medications that work.

But there ARE protocols that work.

The protocols for fixing penile fibrosis are the same as the protocols for fixing fibrosis anywhere in the body.

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These protocols tend to lower stress hormones — especially serotonin.

And they also get oxygen into the tissues.

This is the key to preventing and reversing fibrosis.

So let’s talk about that in today’s newsletter.

Guys are always asking me, “why do I get penile fibrosis?”

I think it’s time everyone had the answer.

Our first stop is going to be in a review of penile fibrosis specifically.

I’m giving you this breakdown piece by piece because it is so helpful in understanding the problem.

And if you don’t have penile fibrosis now, you may have it soon.

That is… unless you do what we’re going to suggest later on in this newsletter.

Aging has a detrimental effect on cavernous tissue and the tunica albuginea of the [PENILE UNIT].

These are the parts of the male member that fill with blood during rockiness.

Those chambers are lined with endothelial cells inside and covered with epithelial cells outside.

Keep that in mind as you read today’s newsletter.

Furthermore, atherosclerosis of the penile vessels that occurs with ageing causes a decrease in penile oxygen tension.

This is very interesting.

It means that less oxygen is reaching the blood vessels in the chambers of the penis.

Less blood means less oxygen.

And less oxygen reaching these tissues creates fibrosis.

…fibrosis but also nitric oxide-cyclic guanosine monophosphate reduction.

Pay attention to the words nitric oxide in the above quote.

We’re going to be talking about nitric oxide again in a moment.

Supposedly the good guy, nitric oxide is actually an emergency compound in the body.

Doctors use it to treat ED and other issues.

But like using a fire extinguisher, you don’t want to use nitric oxide unless it’s an emergency.

You need to minimize nitric oxide rather than maximize it.

The decrease in penile elasticity and compliance are explained by the changes in the ratio of penile collagen that occur with ageing.

Penile collagen is scar-like tissue that is tangled strands of protein.

These start filling up the chambers in the male member.

This is what penile fibrosis is made of.

This is exactly what it is — collagen buildup in the penile tissue.

From here, the study analysis moves its focus to testosterone.

And it makes a very outstanding point.

Testosterone is NOT “just” about desire or about bigger muscles for men.

Numerous recent studies showed that androgen deprivation produces penile tissue atrophy, alterations in nerve structure, alterations in endothelial morphology, increase in deposition of extracellular matrix… in the subtunical region of corpus cavernosum.

In plain English, that means that having low testosterone over time causes the penile tissue to get smaller.

It causes a build up collagen and penile fibrosis and causes the penis to become less sensitive.

This is about when men notice erectile dysfunction and seek treatment.

That treatment often includes nitric oxide, so now I want to talk some more about it.

This is a study that shows:

Hypoxia has been proposed as an important microenvironmental factor in the development of tissue fibrosis.

The fibrosis can be in the penile tissue, the liver, the kidney, the heart, and in the arteries.

Someone with fibrosis in one place will have fibrosis in all the other places too.

Again, the problem is hypoxia.

In this case, it’s not enough oxygen reaching the tissues.

The tissues secrete a compound called hypoxia inducable factor, or HIF-1.

HIF-1 is a compound that causes the body to create new blood vessels in an attempt to fix the lack of oxygen.

While these blood vessels are being formed, the body needs to somehow keep the affected areas alive.

And in comes a flood of nitric oxide to the rescue.

That’s where this study comes in.

The study shows that being chronically short of oxygen in your tissues results in more nitric oxide being produced.

And while the nitric oxide is temporarily necessary, it is very harmful in the long run.

And it results in fibrosis in the tissues.

This is a pretty dire situation, and it is a big reason why you need to get this thing fixed.

The longer the fibrosis is allowed to build, the worse it gets.

And of course, the worse it gets, the more difficult it is to fix.

There is hope for men who haven’t had erections in years, but you have to deal with it right away and not wait around.

The more you wait, the more fibrosis builds, and the more difficult it is to reverse.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.