4 in 10 men have dying livers. And they’re all eating this.

4 in 10 men have dying livers. And they’re all eating this.

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4 in 10 men have dying livers. And they’re all eating this.

“All disease begins in the gut.”

– Hippocrates –

Hippocrates was a Greek doctor. We know him as the father of medicine.

The above quote is one of the most famous in the history of health research.

In recent years, researchers figured out why so many health problems begin in the gut.

Bacterial endotoxins can leak from the gut.

Then, once these bacterial elements get into circulation, they trigger inflammation.

And inflammation leads to disease.

So, Hippocrates was largely correct (2,400 years ago).

But Hippocrates he did miss something…

Recently, scientists discovered that some problems begin in the mouth.

Bacteria in the mouth can lead to systemic inflammation and disease.

A recent study shows that proper oral health can decrease inflammation.

In people suffering from cirrhosis, this led to improved quality of life and improved cognitive function.

These researchers conducted their human study at the Department of Internal Medicine, McGuire VA Medical Centre, Richmond. They published their results in the American Journal of Physiology.

In cirrhosis, scar tissue builds up in the liver and causes disease.

And cirrhosis is an inflammatory process.

“Cirrhosis is associated with a systemic pro-inflammatory milieu, endotoxemia and gut dysbiosis.”

Endotoxemia refers to bacterial elements that leak from your gut into the rest of your system.

But then your liver clears out these bacterial elements.

However, when these bacterial elements overload the liver, it becomes inflamed and damaged – and that leads to cirrhosis.

“The oral cavity could be an additional source of inflammation.”

This study looked at the effect of oral bacteria on cirrhosis and symptoms associated with cirrhosis.

“We aimed to determine the effect of periodontal therapy in cirrhosis through evaluating endotoxemia, inflammation, cognition, and quality of life.”

Can improving oral health lower inflammation in the liver?

The study enrolled people with poor oral health – people diagnosed with chronic gingivitis or periodontitis.

Half of the people enrolled in the study also had cirrhosis of the liver.

The rest of the participants did not have cirrhosis.

And all of the participants were treated by dental experts to improve their oral health.

“Subjects exhibiting chronic gingivitis and/or mild to moderate periodontitis underwent periodontal therapy with follow-up at 30 days.”

The study looked at markers of inflammation before the intervention and again a month later.

“Tests for bacterial endotoxin and immune-inflammatory markers were collected at baseline and day 30.”

The researchers also examined the mental health and cognitive function of the participants.

“Cognitive function and quality of life were also evaluated before intervention a month later.”

Improving oral health lowered inflammation in cirrhotic patients.

“Periodontal treatment improved endotoxin and salivary/serum inflammatory mediators following periodontal therapy.”

The study was too short in duration to assess the effect that lowered inflammation has on cirrhosis.

But the implication is that better oral health will lead to less cirrhosis because it decreases inflammation…

The participants also reported better quality of life after receiving treatment for oral health problems.

“Pre- vs post-therapy quality of life improved in patients following oral interventions.”

Periodontal intervention also improved mental function in patients with cirrhosis.

“Pre vs post-therapy cognition also improved in patients following oral interventions.”

The study tracked another group of cirrhosis patients over the same time period.

But this group did not receive intervention to improve their oral health.

And these patients – not receiving oral health therapy – had increased inflammatory bacteria over that same time period.

“Bacterial endotoxin increased over time in cirrhotics not receiving therapy.”

So without dental treatment, the levels of inflammatory bacteria can increase quite rapidly.

The study shows that addressing oral health can lower inflammation and improve cognitive function in cirrhotic patients.

“This study demonstrates that periodontal therapy in cirrhosis is associated with improved oral and gut dysbiosis, systemic inflammation, and cognitive function.”

You should always consult a healthcare professional about treating and diagnosing health problems.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Periodontal Therapy Favorably Modulates the Oral-Gut-Hepatic Axis in Cirrhosis | American Journal of Physiology-Gastrointestinal and Liver Physiology 
https://www.physiology.org/doi/10.1152/ajpgi.00230.2018 

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