“All health problems are autoimmune”

“All health problems are autoimmune”

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It’s said that almost any chronic condition (high blood pressure, ED, you name it) has an autoimmune cause. And now, researchers from Yale University may have found the underlying cause as well as promising methods for treating these chronic diseases…

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“All health problems are autoimmune”

Scientists have discovered a previously unknown cause of autoimmunity.

Autoimmunity is a process that occurs when the body’s immune system attacks the body’s own tissues.

Arthritis, Hashimoto’s disease, type I diabetes, and celiac disease are all autoimmune diseases.

There are over 100 recognized autoimmune diseases – and there are very few effective treatments.
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This new study reveals one cause of autoimmune diseases and two effective treatments.

This animal study was conducted at Yale University in the United States and published in the Journal of Science.

Scientists had previously noticed a correlation between autoimmune disease and certain types of gut bacteria.

This study set out to discover whether these gut bacteria cause autoimmune diseases.

In prior studies, scientists proved that some of these bacteria can migrate to regions affected by autoimmune diseases.

“We identified a gut microbe that translocates from the gut into the organs of mice with a genetic predisposition to lupus-like autoimmunity…”

The study took some of these suspect bacteria from the gut and put them into different parts of the mice.

Moving the suspect bacteria into other parts of the body triggered autoimmune disease.

“Translocation of the bacteria to the liver and other systemic tissues triggers autoimmune responses in a genetic background predisposing to autoimmunity.”

These results show that bacteria can cause autoimmune diseases.

It remains to be seen whether they are the only cause of autoimmune disease.

For a long time, scientists have noticed the association between leaky gut syndrome and autoimmune diseases.

Leaky gut allows the passage of bacteria from the gut to the rest of the body. Until now the exact relationship was not known.

The scientists discovered that treatment with an antibiotic prevented death from this fatal autoimmune disease.

“Antibiotic treatment prevented mortality in this model.”

The antibiotic stopped the spread of the bacteria in the mice and stopped the spread of autoantibodies.

(Autoantibodies are the source of the damage in autoimmune disease.)

“The antibiotic suppressed growth of bacteria in tissues and eliminated pathogenic autoantibodies.”

Removing autoantibodies means the elimination of the autoimmune disease.

There were other signs that antibiotic treatment reversed other problems with the immune system.

The immune system appeared to be correcting itself after the antibiotic treatment.

The study also tested the effects of a vaccine they created for the bacterially induced autoimmune disease – and it did prevent the disease.

“Autoantibodies and death could be prevented by a vaccine targeting the bacteria.”

The vaccine was delivered into the muscle in order to attack the target bacteria alone – with this method there is no risk of damaging healthy gut bacteria.

Further research with humans then identified the same type of bacteria in the livers of people with an autoimmune liver disease.

“The bacteria were recovered from liver biopsies of autoimmune patients.”

All of this information seems to indicate that at least some autoimmune diseases in humans can be caused by bacteria.

It also indicates that they could be treated with antibiotics.

“Similar processes apparently occur in susceptible humans.”

Bacteria can leak from the gut and travel around the body causing autoimmune disease.

Killing these bacteria with antibiotics could cure the disease.

“These discoveries show that a gut pathobiont can translocate and promote autoimmunity in genetically predisposed hosts.”

These findings are likely to be relevant for people with an autoimmune liver disease and systemic lupus.

Maybe more autoimmune diseases caused by these bacteria or other bacteria – science will have to do more research to find out.

These developments could improve the lives of millions and millions of people worldwide.

You should see a healthcare professional about diagnosing and treating any disorder.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Translocation of a gut pathobiont drives autoimmunity in mice and humans http://science.sciencemag.org/content/359/6380/1156

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