Is soy turning men into pussies?

Is soy turning men into pussies?

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Is soy turning men into pussies?

Many people avoid soy for a number of reasons, but perhaps the least‐known reason to avoid it is its exorphin content.

Like wheat, soy has morphine‐like peptides embedded within its proteins.

These are released upon digestion.

They can numb the brain and nerves, and also release prolactin.

But, unlike wheat, soy exorphins bind to the μ‐opiate receptor, like morphine does, and not to the delta-receptor as enkephalins (our body’s natural pain peptides) and wheat peptides do.

(μ is pronounced Mu.)

Soymorphin is quite similar to beta‐casomorphin, which is released from milk.

Casomorphin is what the brain’s μ‐receptors are supposed to detect, and soy can interfere with this.

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Soymorphin is even closer to the human peptide than the one in cow’s milk.

In fact, the first four amino acids are identical:

You could then expect this to have biological consequences.

And it does…

Soymorphins have been shown to dull nerves, release prolactin, and perhaps even cause mental changes like the near‐identical casomorphin has been shown to do.

Soy protein isolate is particularly enriched with this opiate peptide, and it’s found in nearly everything:

“For example, approximately 60% of ready‐to‐eat meals in American supermarkets contain some amount of soy. These products include not only sauces, meat, and dairy products, but even some kinds of fruit drinks.”

This wasn’t even known until 2007:

The Japanese authors of this study present  the nerve‐deadening effects of soy in a positive light by overusing the term “anxiolytic.”

But seriously, this study was done on isolated guinea pig muscle and a few rats…

The “lack of anxiety” could just as well have been described as “lack of restraint,” “self‐discipline,” or “calmness.”

When talking about green tea or soy, Japanese scientists always use the most positive term to describe any action.

And rat actions can be described in nearly any way you’d like.

But most importantly, soymorphin had been proven to be a powerful opiate – more powerful than the ones found in milk:

Although numbing pain with opiates can be helpful – and even entertaining at times – eating exorphins multiple times a day could lead to hyperprolactinemia…

All opiates release prolactin, which causes visceral weight gain:

The most frequently studied exorphins are the ones found in wheat.

In a series of investigations, wheat peptides have been shown to be powerful prolactin releasers:

The fact that this had been blocked by naloxone proves that it’s working on opiate receptors.

The fact that it’s also blocked by naloxone methobromide – which doesn’t cross the blood-brain barrier – proves that it does this peripherally.

It doesn’t even have to enter the brain to release prolactin.

All opiates do this, whether they act on delta- or μ‐receptors. Even morphine will raise prolactin.

And prolactin causes growth in all cells which have a receptor for it.

The highest concentrations of prolactin receptors are in the breasts and visceral fat of females.

However, males also have prolactin receptors in the same areas.

It has been shown that when abdominal fat lacks the prolactin receptor, it decreases.

This had occurred even in male rats.

Although it hadn’t been measured, you’d expect an associated reduction in breast size.

Prolactin is largely responsible for the female fat deposition pattern you see among many Russian and American men.

“The decrement in body weight in adult PRLR-deficient (prolactin-deficient) mice was accompanied by a reduction in abdominal fat stores. Total abdominal fat content – reflecting subcutaneous, mesenteric, perirenal, and epididymal (male) or periovarian (female) fat stores – was 34% less in mutant males than in wild-type males.”

(They are talking about rats in that quote.)

Although many think estrogen accounts for this – and for manboobs – it probably actually does it by raising prolactin.

This is because estrogen transcribes the prolactin gene.

The correlation between prolactin and body weight had long been known…

But the direction of causation had often seen in reverse.

Some hormones, such as leptin, are released by adipose tissue.

And prolactin has been suggested as one of those hormones.

There have been studies which measured prolactin once a day on subjects of all ages with the full range of thyroid status.

And these studies have produced inconsistent results.

But a far more accurate study – which measured prolactin every ten minutes – left little doubt as to the true role of prolactin.

The study was controlled for age, estrogen level, and thyroid status – and a clear trend emerged:

Just as in rats, prolactin is associated with visceral fat.

“Total daily release is strongly associated with body mass index, in particular with the size of the visceral fat depot.”

So anything that raises prolactin can be expected to do this – opiates from soy and wheat… or estrogen.

And soy is especially troubling in this regard…

Because soy isoflavones are about 100 times more estrogenic than any other polyphenol tested.

Although soy fermentation has reduced exposure to these properties for Japanese men, soy protein isolate isn’t traditionally fermented – and it’s everywhere.

Soy also has a trypsin inhibitor, which can inhibit the digestion of the same peptides that raise prolactin – pretty much ensuring their absorption in long form.

So unfermented soy is not recommended for men who want a thin body shape (though soy sauce in moderation is okay).

“Interestingly, PRL (prolactin) release was particularly associated with the size of the visceral fat area…”

Prolactin is released from the pituitary gland where dopamine actively inhibits it.

The dopaminergic chemical bromocriptine reduces prolactin production, and it can also assist with weight loss.  

But even without using chemicals or other means to modify normal dopamine and estrogen levels, simply avoiding unfermented soy can help with weight loss.

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Matt Cook is editor-in-chief of Daily Medical Discoveries. Matt has been a full time health researcher for 26 years. ABC News interviewed Matt on sexual health issues not long ago. Matt is widely quoted on over 1,000,000 websites. He has over 300,000 daily newsletter readers. Daily Medical Discoveries finds hidden, buried or ignored medical studies through the lens of 100 years of proven science. Matt heads up the editorial team of scientists and health researchers. Each discovery is based upon primary studies from peer reviewed science sources following the Daily Medical Discoveries 7 Step Process to ensure accuracy.
Ohinata, Kousaku. "Soymorphins, novel μ opioid peptides derived from soy β-conglycinin β-subunit, have anxiolytic activities." Bioscience, biotechnology, and biochemistry (2007) https://www.jstage.jst.go.jp/article/bbb/71/10/71_70516/_pdf Chesnokova, E. A. "Behavioral effect of soymorphin-5-amide in rats." Moscow University biological sciences bulletin (2014) https://www.researchgate.net/profile/Ekaterina_Chesnokova/publication/283008969_Behavioral_effect_of_soymorphin-5-amide_in_rats/links/5626074b08aeabddac9261d4.pdf Fanciulli, Giuseppe. "Gluten exorphin B5 stimulates prolactin secretion through opioid receptors located outside the blood-brain barrier." Life sciences (2005) https://www.sciencedirect.com/science/article/pii/S002432050401015X Freemark, Michael. "Body weight and fat deposition in prolactin receptor-deficient mice." Endocrinology (2001) https://academic.oup.com/endo/article-abstract/142/2/532/2988594 Kok, Petra. "Prolactin release is enhanced in proportion to excess visceral fat in obese women." The Journal of Clinical Endocrinology & Metabolism (2004) https://academic.oup.com/jcem/article-abstract/89/9/4445/2844545 

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